被引排行
Research Advance of Breviscapine
WANG Ling,XIAO Yan-hua,HU Qian,PAN Zhi-quan(School of Chemical Engineering and Pharmacy,Wuhan Institute of Technology,Wuhan 430073,China)Breviscapine is the active component of flavone extracted from Erigeron breviscapus(Vant.)Hand.-mazz.which grows peculiarly in the Southwest China,and it is effective in treating cardiovascular and cerebral vessels dieases.This article summarized the research advance of the pharmacological effects,preparation method,determination of content and formulation application of breviscapine.
Surface Coating Technologies of Nano-particles
PAN Rong-jun, He Bao-lin(College of Chemistry and Material Science,South-Central University For Nationalities , Wuhan 430074,China)The present surface coating technologies are discussed by dividing them into three kinds in this paper. And several important methods are described in detail.Something about its use in the future is also analyzed.
A Novel Scaffold Material for Tissue Engineering-Silk
YAN Wen-long, SUN En-jie (Department of Biological Science and Technology , Wuhan University of Technology, Wuhan 430070, China)Tissue engineering(TE) is a new subject developped recently. As one part of tissue engineering, scaffold material plays a key role with its specific characteristics. Silk offers an alternative for scaffolds engineering for its biocompatibility , unique mechanical properties and slow rate of degradation.
Separation and Identification of an Acetic Acid Bacterium and Its Mutation Breeding by Ion Implantation
WU Bin,LI Li,ZHAO Liang-qi(Key Laboratory of Biochemistry and Molecular Engineering of Ministry of Education,Shanxi University,Taiyuan 030006,China)An acetic acid bacterium S12 was isolated from the solid fermentation substrate of Shanxi overmature vinegar.It was identified as Acetobacter pasteurianus.SM12-87 was obtained from the strain S12 by N+ implantation.The conversion rate of alcohol to acetic acid was 88.98%;the yield of total acid and ethyl acetate was 91.67 g·L-1 and 1.143 g·L-1 respectively under 10%(V/V) ethanol,quiescently cultured 5 d at 30℃ by SM12-87.The liquid state seed of SM12-87 was inoculated into the solid fermentation substrate of Shanxi overmature vinegar.The result showed that the yield of acetic acid and ethyl acetate had increased by 20.57% and 41.83% respectively.So,this is a feasible way to optimize the microbial community structure and improve the yield and quality by mutation breeding of the wild functional strain separated from traditional brewing process.
Study on Extraction of Volatile Oil from Zanthoxylum Bungeaum Maxim.in Hanyuan by Supercritical CO2 and Its GC-MS Analysis
LI Yu,ZHOU Xin,DONG Xin-rong (College of Science,Hunan Agricultural University,Changsha 410128,China)In this paper,volatile oil was extracted from Zanthoxylum bungeanum Maxim.in Hanyuan by supercritical CO2 and its constituents were analyzed by GC-MS.The optimum conditions of supercritical CO2 extraction were determined by orthogonal experiment as follows: extraction pressure 30 MPa,extraction temperature 40℃,75% ethanol as entrainer(5% of solid material) and extraction time 2.0 h.The yield of volatile oil was 9.92%.69 Chromatography peaks were obtained by GC-MS and 56 compounds were identified.The main components were linalyl butyrate(30.212%),(1α,3α,4β,6α)-4,7,7-trimethyl-bicycloheptan-3-ol(10.940%),(+)-4-carene(1.826%),4-methylene-1-(1-methylethyl)-bicyclo[3.1.0]hexane(1.109%),β-myrcene(1.170%),limonene(5.784%),3,7-dimethyl-1,6-octadien-3-ol(5.742%),n-hexadecanoic acid(0.914%) and(Z,Z)-9,12-octadecadienoic acid(2.952%),etc.The results indicated that the yield of volatile oil extracted by supercritical CO2 extraction was higher than that by the steam distillation extraction and its constitution was plentiful.
Research Progress of Industrial Status and Synthetic Technology for Polylactide
ZHOU Ai-jun1,LI Chang-cun1,LI Shu-gen2,SHU Di1,YANG Li-xin1(1.Laboratory for Green Chemical Process of Ministry of Education,Wuhan Institute of Technology,Wuhan 430074,China;2.Cyclohexanone Division,Baling Petrochemical Company, SINOPEC Asset Management Corporation,Yueyang 414014,China)The status of polylactide and lactic acid at home and abroad were reviewed.The synthetic technologies of polylactide were introduced,including the ring-opening polymerization method and the direct polycondensation method.The development trend of polylactide industry was prospected.
Preparation and Application Progress of Mesoporous Silica Nanomaterials in Sustained and Controlled Drug Release
WEI Yaqing;LV Jiangwei;REN Jungang;ZHANG Wenjun;WANG Li;With the advantages of large specific surface area,highly-ordered mesoporous structure,easy surface modification,and sustained and controlled drug release,mesoporous silica nanomaterials have been widely used as carrier materials for diagnosis and therapeutic drug delivery.We review the basic characteristics and preparation methods of mesoporous silica nanomaterials,and their applications and influencing factors in sustained and controlled release drug delivery system.The pore size,surface property,and pore structure of mesoporous silica nanomaterials are the main factors affecting the sustained and controlled release properties.Mesoporous silica nanomaterials with different structures can be obtained by changing the preparation process parameters so as to further regulate the drug release performance.Therefore,designing and preparing mesoporous silica nanomaterials with specific structures and sustained and controlled release properties has become one of research hotspots in the pharmaceutical field.
Research Advances in Biosynthesis and Application of Pullulan
WANG Li-heng;Pullulan has a number of favorable properties such as good film-forming,non-toxicity,security and so on.Research status of biosynthesis of pullulan from Aureobasidium pullulans are reviewed.Application advances of pullulan in areas such as food processing,environmental protection,cosmetics are introduced.
Studies on Fermentation Technology for a Strain of Rare Actinomycete Producing Antibiotics
ZHU Yue-jin~(1,2),LONG Zhong-er~(1),HUANG Yun-hong~(1),HUANG Ming-liang~(1),YU Hua-hong~(2)(1.College of Life Science,Jiangxi Normal University,Nanchang 330022,China;2.College of Life Science,Nanchang University,Nanchang 330047,China)The flask fermentation technology and process for a strain of rare actinomycete producing antibiotics,which was isolated from soil and identified primarily as microtetraspora,was studied rudimentarily.The results showed that the optimum medium for antibiotics production from the strain of actinomycete contained starch 2.0%,sucrose 1.3%,peanut meal 3.5%,NaCl 0.10%,K2HPO4 0.01%,Na2SO4 0.01%,(FeSO4)·(7H_2O) 0.001% and CaCO3 0.3%,and the antibiotics yield reached the largest after the actinomycete was cultured for 108 h on a rotary shaker at(200 r)·min-1 under the optimized culture conditions of temperature 28℃,initial pH value 7.7,culture medium amount(20 mL)/(250 mL) flask,and inoculating amount 6%.
Study Development of Nano-ZnO
YE Xiao-yun1,ZHOU Yu-ming2 (1.Department of Materials Science and Engineering,Fujian University of Technology,Fuzhou 350108,China;2.Department of Chemistry and Chemical Engineering,Southeast University,Nanjing 211189,China)As one of the special kind of wide-gap semiconductor materials,nano-ZnO compared with bulk materials has more important properties of electric,magnetic and optic,etc.More and more attentions have been paid on the research and application of nano-ZnO.The current research of ZnO with different nanostructures(grain,wire,belt,rod and other special morphologies) is summarized in this paper.Synthesis technologies of corresponding structures are described in detail.ZnO nanocomposites with special structures are introduced briefly as well.At the same time,the future researches of ZnO nanocomposites with special structures are proposed.