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Gene knock out was a very important technique to study the roles of functional genes,and it was also a very important research branch in the post-genome period.In this paper,the cell basis for gene knock out,the construction of the vector for gene knock out and the screening of the embryonic stem cells where homologous recombination occured,the animal models made after gene knock out,gene knock out and gene rescue,the research progress of gene knock out at home and the problems existed were briefly introduced.
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Basic Information:
China Classification Code:Q78
Citation Information:
[1]LIU Jian-zhong~(1),AO Jing~(1),TIAN Wei-yu~(1),MA Ji-hua~(2)(1.College of Chemical Engineering,Source,and Environment,Wuhan University of Science and Technology,Wuhan 430081,China,2.College of Medical Science,Wuhan University of Science and Technology,Wuhan 430081,China).The Research Progress in Gene Knock Out[J].Chemistry ＆ Bioengineering,2006(02):4-6.
Fund Information:
湖北省教育厅青年基金资助课题(2004D016)
2006-02-25
2006-02-25