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We prepared SiO2@Au-GOx Janus micromotors by sputtering a gold(Au) layer on the surface of SiO2 microspheres by using magnetron sputtering technique and loading with glucose oxidase(GOx).Moreover, we characterized the morphology and structure of the micromotors by field emission scanning electron microscope and inverted fluorescent microscope, and evaluated the motion performance.Furthermore, we investigated the chemotactic performance of the micromotors through microfluidic channel.The results show that SiO2@Au-GOx micromotors are formed by half-coating the Au layer on the surface of SiO2 microspheres to form a Janus structure and loading GOx on the opposite side, with a diameter of about 3 μm.When no glucose is added to the right side of the microfluidic channel, the motion range, displacement of mass center, and directionality of the micromotors all show a trend of first increasing and then decreasing with the increase of glucose concentration in the agar on the left side, and the best chemotactic performance is achieved at a concentration of 200 mmol·L-1.When the concentration gradient difference between the two sides of the microfluidic channel is the same, the micromotors show the same motion tendency with the increase of the initial glucose concentration on the right side, indicating that the size of the glucose concentration gradient field and the initial glucose concentration can affect the chemotactic performance of the micromotors.
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Basic Information:
China Classification Code:TB381;Q503
Citation Information:
[1]SI Yanbing,GUAN Qiaoxin,XU Leilei.Chemotactic Performance of Glucose Oxidase-Driven Micromotors[J].Chemistry ＆ Bioengineering,2026,43(07):26-30+38.
Fund Information:
国家自然科学基金项目(21975195)
2024-10-19
2024
2024-11-28
2024
1
2026-07-06
2026-07-06