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2026, 05, v.43 1-8+22
Mechanism and Application Progress of Novel Hydrogel Adjuvants
Email: shujianhong@zstu.edu.cn;
DOI:
Received:   2024-11-03
Received Year:   2024
Accepted:   2025-02-27
Accepted Year:   2025
Review Duration(Year):   1
Published:   2026-05-13
Publication Date:   2026-05-13
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Abstract:

Adjuvants are important components of vaccines, which can significantly enhance the immunogenicity of antigens.Hydrogel adjuvants have three-dimensional network structures formed by the physical and chemical cross-linking of hydrophilic polymer materials.Hydrogel adjuvants are favored for their advantages such as sustained-release property, controllability, and safety.Their excellent immune enhancement effect and delivery performance can effectively prolong the efficacy of vaccines, thereby promoting the research and development of novel vaccines.In this paper, we summarize the action mechanism of hydrogel adjuvants, and review the application progress of natural polymer, synthetic polymer, and hybrid polymer hydrogel adjuvants in the field of vaccines, which provides a theoretical support for in-depth research and application of hydrogel adjuvants in the field of vaccine research and development.

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Basic Information:

China Classification Code:TQ427.26;R392

Citation Information:

[1]TU Yiting,XU Shangen,WANG Afei ,et al.Mechanism and Application Progress of Novel Hydrogel Adjuvants[J].Chemistry & Bioengineering,2026,43(05):1-8+22.

Fund Information:

国家自然科学基金项目(32370987); 浙江省“尖兵”“领雁”研发攻关计划项目(2022C02031); 台州市科技计划项目(23gya02)

Received:  

2024-11-03

Received Year:  

2024

Accepted:  

2025-02-27

Accepted Year:  

2025

Review Duration(Year):  

1

Published:  

2026-05-13

Publication Date:  

2026-05-13

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